Effects Of Prp On Bone Healing In Human Clinical Studies Download Table

Effects Of Prp On Bone Healing In Human Clinical Studies Download Table Introduction. bone tissue is a major part of the musculoskeletal system and provides the framework which supports the body and maintains its shape (1–3).although bone tissue has the potential for spontaneous healing after injuries, the regenerative capacity of bone tissue is limited by many factors, such as age, type of fracture, genetic bone disorder (4–6). The average number of patients per study was 52±52, with a range of 10 to 200 patients, and an average follow up period of approximately 16±15 months (range 2–72 months). of the clinical studies, 19 (79%) reported favorable clinical outcomes associated with the use of prp to improve bone healing.

Effects Of Prp On Bone Healing In Human Clinical Studies Download Table Download table | effects of prp on bone healing in human clinical studies. from publication: platelet rich plasma for bone healing and regeneration | introduction: successful healing of large bone. The effect of local application of autologous platelet rich plasma (prp) on bone healing in combination with the use of titanium implants with 2 different surface configurations was investigated. Based on the findings of the aforementioned studies, prp mediated effects on tendon healing could be secondary to improved vascularity (with careful consideration of the potential degradative properties of angiogenesis) and or the anti inflammatory effects of growth factors known to increase with exogenous administration of platelets. Method: this was a randomized double blind placebo controlled clinical trial being performed in a 12 month period. we included 75 adult (>18 years) patients suffering from long bone (femur, tibia, humerus and ulna) non union fracture who were randomly assigned to receive 5ml prp (n=37) or 5ml normal saline as placebo (n=38) in the site of fracture after intramedullary nailing or open reduction.